Cargando…

Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients

INTRODUCTION: Systemic lupus erythematosus (SLE) is characterized by B cell hyper-activation and auto-reactivity resulting in pathogenic auto-antibody generation. The phenotypic analysis of blood B cell subsets can be used to understand these alterations. METHODS: The combined detection of CD19, CD2...

Descripción completa

Detalles Bibliográficos
Autores principales: Rodríguez-Bayona, Beatriz, Ramos-Amaya, Ana, Pérez-Venegas, José J, Rodríguez , Carmen, Brieva, José A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911899/
https://www.ncbi.nlm.nih.gov/pubmed/20525218
http://dx.doi.org/10.1186/ar3042