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Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients

INTRODUCTION: Systemic lupus erythematosus (SLE) is characterized by B cell hyper-activation and auto-reactivity resulting in pathogenic auto-antibody generation. The phenotypic analysis of blood B cell subsets can be used to understand these alterations. METHODS: The combined detection of CD19, CD2...

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Detalles Bibliográficos
Autores principales:	Rodríguez-Bayona, Beatriz, Ramos-Amaya, Ana, Pérez-Venegas, José J, Rodríguez , Carmen, Brieva, José A
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911899/ https://www.ncbi.nlm.nih.gov/pubmed/20525218 http://dx.doi.org/10.1186/ar3042

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