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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

INTRODUCTION: Increasing evidence support the regulatory role of leptin in osteoarthritis (OA). As high circulating concentrations of leptin disrupt the physiological function of the adipokine in obese individuals, the current study has been undertaken to determine whether the elevated levels of lep...

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Detalles Bibliográficos
Autores principales: Pallu, Stéphane, Francin, Pierre-Jean, Guillaume, Cécile, Gegout-Pottie, Pascale, Netter, Patrick, Mainard, Didier, Terlain, Bernard, Presle, Nathalie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911905/
https://www.ncbi.nlm.nih.gov/pubmed/20534145
http://dx.doi.org/10.1186/ar3048