Cargando…
Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis
INTRODUCTION: Increasing evidence support the regulatory role of leptin in osteoarthritis (OA). As high circulating concentrations of leptin disrupt the physiological function of the adipokine in obese individuals, the current study has been undertaken to determine whether the elevated levels of lep...
Autores principales: | Pallu, Stéphane, Francin, Pierre-Jean, Guillaume, Cécile, Gegout-Pottie, Pascale, Netter, Patrick, Mainard, Didier, Terlain, Bernard, Presle, Nathalie |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911905/ https://www.ncbi.nlm.nih.gov/pubmed/20534145 http://dx.doi.org/10.1186/ar3048 |
Ejemplares similares
-
Is leptin the link between obesity and osteoarthritis?
por: Pottie, P, et al.
Publicado: (2004) -
Overexpression and induction of heat shock protein 70 protect chondrocytes from cell death in vitro and in vivo
por: Grossin, L, et al.
Publicado: (2003) -
Overexpression and induction of heat shock protein (Hsp) 70 protects in vitro and in vivo from mono-iodoacetate (MIA)-induced chondrocytes death
por: Cournil, C, et al.
Publicado: (2001) -
Contrasting effects of peroxisome-proliferator-activated receptor (PPAR)γ agonists on membrane-associated prostaglandin E(2 )synthase-1 in IL-1β-stimulated rat chondrocytes: evidence for PPARγ-independent inhibition by 15-deoxy-Δ(12,14)prostaglandin J(2)
por: Bianchi, Arnaud, et al.
Publicado: (2005) -
Xylosyltransferase-I Regulates Glycosaminoglycan Synthesis during the Pathogenic Process of Human Osteoarthritis
por: Venkatesan, Narayanan, et al.
Publicado: (2012)