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Peripheral primitive neuroectodermal tumor causing cauda equina syndrome with destruction of L5 vertebra

A 24-year-old male patient presented with cauda equina lesion symptoms. His clinicoradiological examination including X-rays, CT scan and MRI revealed destruction of L(5) vertebral body, pedicle and a mass extending to lateral recess and left intervertebral foramina causing pressure over the thecal...

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Detalles Bibliográficos
Autores principales: Dhatt, Sarvdeep, Dhillon, Mandeep S, Tripathy, Sujit K, Goyal, Tarun, Jagadeesh, V
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911938/
https://www.ncbi.nlm.nih.gov/pubmed/20697491
http://dx.doi.org/10.4103/0019-5413.65153
Descripción
Sumario:A 24-year-old male patient presented with cauda equina lesion symptoms. His clinicoradiological examination including X-rays, CT scan and MRI revealed destruction of L(5) vertebral body, pedicle and a mass extending to lateral recess and left intervertebral foramina causing pressure over the thecal sac. A CT guided FNAC was inconclusive. Open biopsy and hemilaminectomy of L(5) vertebra was performed. Histopathology and immunocytochemical analysis revealed it to be primitive neuroectodermal tumor. Patient was given chemotherapy and radiation therapy. His lower limb power improved by grade I post operatively and at 2 years follow-up bowel/bladder recovery was noticed. Patient died after 2.5 years of surgery because of pulmonary metastasis.