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The RCK1 domain of the human BK(Ca) channel transduces Ca(2+) binding into structural rearrangements

Large-conductance voltage- and Ca(2+)-activated K(+) (BK(Ca)) channels play a fundamental role in cellular function by integrating information from their voltage and Ca(2+) sensors to control membrane potential and Ca(2+) homeostasis. The molecular mechanism of Ca(2+)-dependent regulation of BK(Ca)...

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Detalles Bibliográficos
Autores principales: Yusifov, Taleh, Javaherian, Anoosh D., Pantazis, Antonios, Gandhi, Chris S., Olcese, Riccardo
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912072/
https://www.ncbi.nlm.nih.gov/pubmed/20624858
http://dx.doi.org/10.1085/jgp.200910374