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ROS accumulation and IGF-IR inhibition contribute to fenofibrate/PPARα -mediated inhibition of Glioma cell motility in vitro

BACKGROUND: Glioblastomas are characterized by rapid cell growth, aggressive CNS infiltration, and are resistant to all known anticancer regimens. Recent studies indicate that fibrates and statins possess anticancer potential. Fenofibrate is a potent agonist of peroxisome proliferator activated rece...

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Detalles Bibliográficos
Autores principales:	Drukala, Justyna, Urbanska, Katarzyna, Wilk, Anna, Grabacka, Maja, Wybieralska, Ewa, Del Valle, Luis, Madeja, Zbigniew, Reiss, Krzysztof
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912247/ https://www.ncbi.nlm.nih.gov/pubmed/20569465 http://dx.doi.org/10.1186/1476-4598-9-159

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