Cargando…

Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice

BACKGROUND: The importance of cell-surface nucleolin in cancer biology was recently highlighted by studies showing that ligands of nucleolin play critical role in tumorigenesis and angiogenesis. By using a specific antagonist that binds the C-terminal tail of nucleolin, the HB-19 pseudopeptide, we r...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Khoury, Diala, Destouches, Damien, Lengagne, Renée, Krust, Bernard, Hamma-Kourbali, Yamina, Garcette, Marylène, Niro, Sandra, Kato, Masashi, Briand, Jean-Paul, Courty, José, Hovanessian, Ara G, Prévost-Blondel, Armelle
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912263/ https://www.ncbi.nlm.nih.gov/pubmed/20573279 http://dx.doi.org/10.1186/1471-2407-10-325

Ejemplares similares

Suppression of Tumor Growth and Angiogenesis by a Specific Antagonist of the Cell-Surface Expressed Nucleolin
por: Destouches, Damien, et al.
Publicado: (2008)

Targeting surface nucleolin with multivalent HB-19 and related Nucant pseudopeptides results in distinct inhibitory mechanisms depending on the malignant tumor cell type
por: Krust, Bernard, et al.
Publicado: (2011)

Nucleolin mediates the antiangiogenesis effect of the pseudopeptide N6L
por: Birmpas, Charalampos, et al.
Publicado: (2012)

The pseudopeptide HB-19 binds to cell surface nucleolin and inhibits angiogenesis
por: Birmpas, Charalampos, et al.
Publicado: (2012)

Multivalent cationic pseudopeptide polyplexes as a tool for cancer therapy
por: Diamantopoulou, Zoi, et al.
Publicado: (2017)

Surface Expressed Nucleolin Is Constantly Induced in Tumor Cells to Mediate Calcium-Dependent Ligand Internalization
por: Hovanessian, Ara G., et al.
Publicado: (2010)

Pleiotrophin Exerts Its Migration and Invasion Effect through the Neuropilin-1 Pathway
por: Elahouel, Rania, et al.
Publicado: (2015)

T Cells Contribute to Tumor Progression by Favoring Pro-Tumoral Properties of Intra-Tumoral Myeloid Cells in a Mouse Model for Spontaneous Melanoma
por: Lengagne, Renée, et al.
Publicado: (2011)

A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ
por: Diamantopoulou, Zoi, et al.
Publicado: (2010)

Antitumor and Angiostatic Activities of the Antimicrobial Peptide Dermaseptin B2
por: van Zoggel, Hanneke, et al.
Publicado: (2012)

The synthetic peptide P111-136 derived from the C-terminal domain of heparin affin regulatory peptide inhibits tumour growth of prostate cancer PC-3 cells
por: Hamma-Kourbali, Yamina, et al.
Publicado: (2011)

A novel receptor – ligand pathway for entry of Francisella tularensis in monocyte-like THP-1 cells: interaction between surface nucleolin and bacterial elongation factor Tu
por: Barel, Monique, et al.
Publicado: (2008)

Nitric Oxide Synthase 2 Improves Proliferation and Glycolysis of Peripheral γδ T Cells
por: Douguet, Laetitia, et al.
Publicado: (2016)

Heterocycles in Peptidomimetics and Pseudopeptides: Design and Synthesis (†)
por: Cerminara, Iole, et al.
Publicado: (2012)

Overexpression of Nucleolin and Associated Genes in Prostate Cancer
por: Firlej, Virginie, et al.
Publicado: (2022)

Hair graying with aging in mice carrying oncogenic RET
por: Iida, Machiko, et al.
Publicado: (2020)

Propranolol induces a favourable shift of anti-tumor immunity in a murine spontaneous model of melanoma
por: Wrobel, Ludovic Jean, et al.
Publicado: (2016)

New building blocks or dendritic pseudopeptides for metal chelating
por: Ruan, Min, et al.
Publicado: (2016)

Tuning Mechanical Properties of Pseudopeptide Supramolecular Hydrogels by Graphene Doping
por: Giuri, Demetra, et al.
Publicado: (2019)

Nucleolin antagonist triggers autophagic cell death in human glioblastoma primary cells and decreased in vivo tumor growth in orthotopic brain tumor model
por: Benedetti, Elisabetta, et al.
Publicado: (2015)

Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin
por: Koutsioumpa, Marina, et al.
Publicado: (2012)

d-Amino Acid Pseudopeptides as Potential Amyloid-Beta Aggregation Inhibitors
por: Mehrazma, Banafsheh, et al.
Publicado: (2018)

Application of the N-Dibenzyl Protective Group in the Preparation of β-Lactam Pseudopeptides
por: Frlan, Rok, et al.
Publicado: (2019)

Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages
por: Tapia, Lucía, et al.
Publicado: (2021)

Continuous Flow Processes as an Enabling Tool for the Synthesis of Constrained Pseudopeptidic Macrocycles
por: Esteve, Ferran, et al.
Publicado: (2022)

Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression
por: Ponzo, Matteo, et al.
Publicado: (2022)

Novel synthesis of pseudopeptides bearing a difluoromethyl group by Ugi reaction and desulfanylation
por: Wu, Jingjing, et al.
Publicado: (2011)

A Pseudopeptide Polymer Micelle Used for Asymmetric Catalysis of the Aldol Reaction in Water
por: Liu, Keyuan, et al.
Publicado: (2018)

Pseudopeptide Amyloid Aggregation Inhibitors: In Silico, Single Molecule and Cell Viability Studies
por: Robinson, Morgan, et al.
Publicado: (2021)

Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans
por: Dos Santos, Célia, et al.
Publicado: (2017)

Antitumor Activity and Mechanism of Action of Hormonotoxin, an LHRH Analog Conjugated to Dermaseptin-B2, a Multifunctional Antimicrobial Peptide
por: Couty, Mickael, et al.
Publicado: (2021)

The Neuropilin-1/PKC axis promotes neuroendocrine differentiation and drug resistance of prostate cancer
por: Blanc, Charly, et al.
Publicado: (2022)

ATP-dependent ligases in trypanothione biosynthesis – kinetics of catalysis and inhibition by phosphinic acid pseudopeptides
por: Oza, Sandra L, et al.
Publicado: (2008)

Development of Reduced Peptide Bond Pseudopeptide Michael Acceptors for the Treatment of Human African Trypanosomiasis
por: Previti, Santo, et al.
Publicado: (2022)

AS1411 Nucleolin-Specific Binding Aptamers Reduce Pathological Angiogenesis through Inhibition of Nucleolin Phosphorylation
por: Iturriaga-Goyon, Emilio, et al.
Publicado: (2021)

Nucleolin Aptamer N6L Reprograms the Translational Machinery and Acts Synergistically with mTORi to Inhibit Pancreatic Cancer Proliferation
por: Chalabi-Dchar, Mounira, et al.
Publicado: (2021)

The Nucleolin Antagonist N6L Inhibits LINE1 Retrotransposon Activity in Non-Small Cell Lung Carcinoma Cells
por: Ramos, Kenneth S., et al.
Publicado: (2020)

Carboxymethyl benzylamide dextran inhibits angiogenesis and growth of VEGF-overexpressing human epidermoid carcinoma xenograft in nude mice
por: Hamma-Kourbali, Y, et al.
Publicado: (2003)

Expression of Nucleolin Affects Microtubule Dynamics
por: Gaume, Xavier, et al.
Publicado: (2016)

Suppression of Tumor Growth in Mice by Rationally Designed Pseudopeptide Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase()
por: Jackson, Kenneth W., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4kpqkfdsh3voj9s1vnu4dbvahl