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Putative contribution of CD56 positive cells in cetuximab treatment efficacy in first-line metastatic colorectal cancer patients

BACKGROUND: Activity of cetuximab, a chimeric monoclonal antibody targeting the epidermal growth factor receptor, is largely attributed to its direct antiproliferative and proapoptotic effects. Antibody-dependent cell-mediated cytotoxicity (ADCC) could be another possible mechanism of cetuximab anti...

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Detalles Bibliográficos
Autores principales:	Maréchal, Raphaël, De Schutter, Jef, Nagy, Nathalie, Demetter, Pieter, Lemmers, Arnaud, Devière, Jacques, Salmon, Isabelle, Tejpar, Sabine, Van Laethem, Jean-Luc
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912265/ https://www.ncbi.nlm.nih.gov/pubmed/20591136 http://dx.doi.org/10.1186/1471-2407-10-340

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