Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature

BACKGROUND AND CASE PRESENTATION: A patient with nevoid basal cell carcinoma syndrome (Gorlin syndrome) presented with two unusual clinical features, i.e. adenocarcinoma of the small bowel and extensive mesenchymal proliferation of the lower gastrointestinal tract. CONCLUSIONS: We discuss the possib...

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Autores principales: Prodinger, Peter M, Sarbia, Mario, Maßmann, Jörg, Straka, Christian, Meyer, Günther, Steinlein, Ortrud K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912266/
https://www.ncbi.nlm.nih.gov/pubmed/20609239
http://dx.doi.org/10.1186/1471-2407-10-360
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author Prodinger, Peter M
Sarbia, Mario
Maßmann, Jörg
Straka, Christian
Meyer, Günther
Steinlein, Ortrud K
author_facet Prodinger, Peter M
Sarbia, Mario
Maßmann, Jörg
Straka, Christian
Meyer, Günther
Steinlein, Ortrud K
author_sort Prodinger, Peter M
collection PubMed
description BACKGROUND AND CASE PRESENTATION: A patient with nevoid basal cell carcinoma syndrome (Gorlin syndrome) presented with two unusual clinical features, i.e. adenocarcinoma of the small bowel and extensive mesenchymal proliferation of the lower gastrointestinal tract. CONCLUSIONS: We discuss the possibility that these two features are pathogenetically linked to the formerly undescribed patient's PTCH germ line mutation.
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spelling pubmed-29122662010-07-30 Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature Prodinger, Peter M Sarbia, Mario Maßmann, Jörg Straka, Christian Meyer, Günther Steinlein, Ortrud K BMC Cancer Case Report BACKGROUND AND CASE PRESENTATION: A patient with nevoid basal cell carcinoma syndrome (Gorlin syndrome) presented with two unusual clinical features, i.e. adenocarcinoma of the small bowel and extensive mesenchymal proliferation of the lower gastrointestinal tract. CONCLUSIONS: We discuss the possibility that these two features are pathogenetically linked to the formerly undescribed patient's PTCH germ line mutation. BioMed Central 2010-07-07 /pmc/articles/PMC2912266/ /pubmed/20609239 http://dx.doi.org/10.1186/1471-2407-10-360 Text en Copyright ©2010 Prodinger et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Prodinger, Peter M
Sarbia, Mario
Maßmann, Jörg
Straka, Christian
Meyer, Günther
Steinlein, Ortrud K
Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
title Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
title_full Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
title_fullStr Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
title_full_unstemmed Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
title_short Gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
title_sort gorlin syndrome associated with small bowel carcinoma and mesenchymal proliferation of the gastrointestinal tract: case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912266/
https://www.ncbi.nlm.nih.gov/pubmed/20609239
http://dx.doi.org/10.1186/1471-2407-10-360
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