More Than 1,001 Problems with Protein Domain Databases: Transmembrane Regions, Signal Peptides and the Issue of Sequence Homology

Large-scale genome sequencing gained general importance for life science because functional annotation of otherwise experimentally uncharacterized sequences is made possible by the theory of biomolecular sequence homology. Historically, the paradigm of similarity of protein sequences implying common...

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Detalles Bibliográficos
Autores principales: Wong, Wing-Cheong, Maurer-Stroh, Sebastian, Eisenhaber, Frank
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912341/
https://www.ncbi.nlm.nih.gov/pubmed/20686689
http://dx.doi.org/10.1371/journal.pcbi.1000867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912341/
https://www.ncbi.nlm.nih.gov/pubmed/20686689
http://dx.doi.org/10.1371/journal.pcbi.1000867

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