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Emi2-mediated Inhibition of E2-substrate Ubiquitin Transfer by the Anaphase-promoting Complex/Cyclosome through a D-Box–independent Mechanism

Vertebrate eggs are arrested at Metaphase II by Emi2, the meiotic anaphase-promoting complex/cyclosome (APC/C) inhibitor. Although the importance of Emi2 during oocyte maturation has been widely recognized and its regulation extensively studied, its mechanism of action remained elusive. Many APC/C i...

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Detalles Bibliográficos
Autores principales:	Tang, Wanli, Wu, Judy Qiju, Chen, Chen, Yang, Chih-Sheng, Guo, Jessie Yanxiang, Freel, Christopher D., Kornbluth, Sally
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912346/ https://www.ncbi.nlm.nih.gov/pubmed/20534816 http://dx.doi.org/10.1091/mbc.E09-08-0708

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