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Clioquinol Inhibits Zinc-Triggered Caspase Activation in the Hippocampal CA1 Region of a Global Ischemic Gerbil Model

BACKGROUND: Excessive release of chelatable zinc from excitatory synaptic vesicles is involved in the pathogenesis of selective neuronal cell death following transient forebrain ischemia. The present study was designed to examine the neuroprotective effect of a membrane-permeable zinc chelator, clio...

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Detalles Bibliográficos
Autores principales:	Wang, Tao, Zheng, Wei, Xu, He, Zhou, Jia-Min, Wang, Zhan-You
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912365/ https://www.ncbi.nlm.nih.gov/pubmed/20686690 http://dx.doi.org/10.1371/journal.pone.0011888

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