Genome-Wide Analysis Reveals Novel Genes Essential for Heme Homeostasis in Caenorhabditis elegans

Heme is a cofactor in proteins that function in almost all sub-cellular compartments and in many diverse biological processes. Heme is produced by a conserved biosynthetic pathway that is highly regulated to prevent the accumulation of heme—a cytotoxic, hydrophobic tetrapyrrole. Caenorhabditis elega...

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Detalles Bibliográficos
Autores principales: Severance, Scott, Rajagopal, Abbhirami, Rao, Anita U., Cerqueira, Gustavo C., Mitreva, Makedonka, El-Sayed, Najib M., Krause, Michael, Hamza, Iqbal
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912396/
https://www.ncbi.nlm.nih.gov/pubmed/20686661
http://dx.doi.org/10.1371/journal.pgen.1001044

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