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Back to the Future: Studying Cholera Pathogenesis Using Infant Rabbits
Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V. cholerae into 3-day-old rabbits pretreated with cimetidine led to lethal, watery diarrhea in virtually all rabbits....
Autores principales: | Ritchie, Jennifer M., Rui, Haopeng, Bronson, Roderick T., Waldor, Matthew K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912669/ https://www.ncbi.nlm.nih.gov/pubmed/20689747 http://dx.doi.org/10.1128/mBio.00047-10 |
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