Insulators and imprinting from flies to mammals

The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2 locus. MacDonald and colleagues now report in BMC Biology that the mechanisms responsible for maintaining the imprinted state in Drosophila may be evolutionarily conserved and t...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Chunhui, Corces, Victor G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912829/
https://www.ncbi.nlm.nih.gov/pubmed/20687908
http://dx.doi.org/10.1186/1741-7007-8-104
_version_ 1782184630485516288
author Hou, Chunhui
Corces, Victor G
author_facet Hou, Chunhui
Corces, Victor G
author_sort Hou, Chunhui
collection PubMed
description The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2 locus. MacDonald and colleagues now report in BMC Biology that the mechanisms responsible for maintaining the imprinted state in Drosophila may be evolutionarily conserved and that CTCF may also play a critical role in this process. See research article http://www.biomedcentral.com/1741-7007/8/105
format Text
id pubmed-2912829
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-29128292010-07-31 Insulators and imprinting from flies to mammals Hou, Chunhui Corces, Victor G BMC Biol Commentary The nuclear factor CTCF has been shown to be necessary for the maintenance of genetic imprinting at the mammalian H19/Igf2 locus. MacDonald and colleagues now report in BMC Biology that the mechanisms responsible for maintaining the imprinted state in Drosophila may be evolutionarily conserved and that CTCF may also play a critical role in this process. See research article http://www.biomedcentral.com/1741-7007/8/105 BioMed Central 2010-07-30 /pmc/articles/PMC2912829/ /pubmed/20687908 http://dx.doi.org/10.1186/1741-7007-8-104 Text en Copyright ©2010 Hou and Corces; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary
Hou, Chunhui
Corces, Victor G
Insulators and imprinting from flies to mammals
title Insulators and imprinting from flies to mammals
title_full Insulators and imprinting from flies to mammals
title_fullStr Insulators and imprinting from flies to mammals
title_full_unstemmed Insulators and imprinting from flies to mammals
title_short Insulators and imprinting from flies to mammals
title_sort insulators and imprinting from flies to mammals
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912829/
https://www.ncbi.nlm.nih.gov/pubmed/20687908
http://dx.doi.org/10.1186/1741-7007-8-104
work_keys_str_mv AT houchunhui insulatorsandimprintingfromfliestomammals
AT corcesvictorg insulatorsandimprintingfromfliestomammals

Ejemplares similares