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Targeted overexpression of human α-synuclein in oligodendroglia induces lesions linked to MSA -like progressive autonomic failure
Multiple system atrophy (MSA) is a rare neurodegenerative disease of undetermined cause manifesting with progressive autonomic failure (AF), cerebellar ataxia and parkinsonism due to neuronal loss in multiple brain areas associated with (oligodendro)glial cytoplasmic α-synuclein (αSYN) inclusions (G...
Autores principales: | Stemberger, Sylvia, Poewe, Werner, Wenning, Gregor K., Stefanova, Nadia |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913120/ https://www.ncbi.nlm.nih.gov/pubmed/20493840 http://dx.doi.org/10.1016/j.expneurol.2010.05.008 |
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