CD4+ T-lymphocyte telomere length is related to fibrosis stage, clinical outcome and treatment response in chronic hepatitis C virus infection

BACKGROUND & AIMS: Increasing age is associated with impaired immune function and in chronic HCV infection specifically, with progressive fibrosis, liver failure, HCC and impaired responses to antiviral therapy. T-lymphocyte telomere length declines with age. We hypothesised that shorter T-lymph...

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Detalles Bibliográficos
Autores principales: Hoare, Matthew, Gelson, William T.H., Das, Abhi, Fletcher, Jean M., Davies, Susan E., Curran, Martin D., Vowler, Sarah L., Maini, Mala K., Akbar, Arne N., Alexander, Graeme J.M.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913243/
https://www.ncbi.nlm.nih.gov/pubmed/20462651
http://dx.doi.org/10.1016/j.jhep.2010.03.005

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