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Clustering phenotype populations by genome-wide RNAi and multiparametric imaging
Genetic screens for phenotypic similarity have made key contributions to associating genes with biological processes. With RNA interference (RNAi), highly parallel phenotyping of loss-of-function effects in cells has become feasible. One of the current challenges however is the computational categor...
Autores principales: | Fuchs, Florian, Pau, Gregoire, Kranz, Dominique, Sklyar, Oleg, Budjan, Christoph, Steinbrink, Sandra, Horn, Thomas, Pedal, Angelika, Huber, Wolfgang, Boutros, Michael |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913390/ https://www.ncbi.nlm.nih.gov/pubmed/20531400 http://dx.doi.org/10.1038/msb.2010.25 |
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