Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32

To identify susceptibility loci for non-Hodgkin lymphoma (NHL) subtypes, we conducted a three-stage genome-wide association study. We identified two variants associated with follicular lymphoma (FL) in 1,465 FL cases/6,958 controls at 6p21.32 (rs10484561, rs7755224, r(2)=1.0; combined p-values=1.12×...

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Autores principales: Conde, Lucia, Halperin, Eran, Akers, Nicholas K., Brown, Kevin M., Smedby, Karin E., Rothman, Nathaniel, Nieters, Alexandra, Slager, Susan L., Brooks-Wilson, Angela, Agana, Luz, Riby, Jacques, Liu, Jianjun, Adami, Hans-Olov, Darabi, Hatef, Hjalgrim, Henrik, Low, Hui-Qi, Humphreys, Keith, Melbye, Mads, Chang, Ellen T., Glimelius, Bengt, Cozen, Wendy, Davis, Scott, Hartge, Patricia, Morton, Lindsay M., Schenk, Maryjean, Wang, Sophia S., Armstrong, Bruce, Kricker, Anne, Milliken, Sam, Purdue, Mark P., Vajdic, Claire M., Boyle, Peter, Lan, Qing, Zahm, Shelia H., Zhang, Yawei, Zheng, Tongzhang, Becker, Nikolaus, Benavente, Yolanda, Boffetta, Paolo, Brennan, Paul, Butterbach, Katja, Cocco, Pierluigi, Foretova, Lenka, Maynadié, Marc, de Sanjosé, Silvia, Staines, Anthony, Spinelli, John J., Achenbach, Sara J., Call, Timothy G., Camp, Nicola J., Caporaso, Neil E., Cerhan, James R., Cunningham, Julie M., Goldin, Lynn R, Hanson, Curtis A., Kay, Neil E., Lanasa, Mark C., Leis, Jose F., Marti, Gerald E., Rabe, Kari G., Rassenti, Laura Z., Spector, Logan G., Strom, Sara S., Vachon, Celine M., Weinberg, J. Brice, Holly, Elizabeth A., Chanock, Stephen, Smith, Martyn T., Bracci, Paige M., Skibola, Christine F.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913472/
https://www.ncbi.nlm.nih.gov/pubmed/20639881
http://dx.doi.org/10.1038/ng.626

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