Efficacy and tolerability of injectable sodium valproate in patients with mania

BACKGROUND: Sodium valproate is among the newer mood stabilizers and is also an anticonvulsant. AIM: To assess the effect of intravenous sodium valproate in patients with acute manic episodes of bipolar disorder. METHODS: A 1-week open trial was conducted in the year 2004–2005 at the emergency ward...

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Detalles Bibliográficos
Autores principales: Solanki, R. K., Singh, Paramjeet, Khandelwal, Renu, Midha, Aarti
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2006
Materias:
Brief Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913561/
https://www.ncbi.nlm.nih.gov/pubmed/20703399
http://dx.doi.org/10.4103/0019-5545.31603
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author Solanki, R. K.
Singh, Paramjeet
Khandelwal, Renu
Midha, Aarti
author_facet Solanki, R. K.
Singh, Paramjeet
Khandelwal, Renu
Midha, Aarti
author_sort Solanki, R. K.
collection PubMed
description BACKGROUND: Sodium valproate is among the newer mood stabilizers and is also an anticonvulsant. AIM: To assess the effect of intravenous sodium valproate in patients with acute manic episodes of bipolar disorder. METHODS: A 1-week open trial was conducted in the year 2004–2005 at the emergency ward of the Psychiatric Centre, SMS Medical College, Jaipur, in which 30 patients participated. CONCLUSION: Substantial improvement was seen. No major side-effects were noted except marginal elevation of the SGOT and SGPT. The findings suggest that injectable sodium valproate is a safe and effective mood stabilizer for patients with mania.
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spelling pubmed-29135612010-08-11 Efficacy and tolerability of injectable sodium valproate in patients with mania Solanki, R. K. Singh, Paramjeet Khandelwal, Renu Midha, Aarti Indian J Psychiatry Brief Research Communication BACKGROUND: Sodium valproate is among the newer mood stabilizers and is also an anticonvulsant. AIM: To assess the effect of intravenous sodium valproate in patients with acute manic episodes of bipolar disorder. METHODS: A 1-week open trial was conducted in the year 2004–2005 at the emergency ward of the Psychiatric Centre, SMS Medical College, Jaipur, in which 30 patients participated. CONCLUSION: Substantial improvement was seen. No major side-effects were noted except marginal elevation of the SGOT and SGPT. The findings suggest that injectable sodium valproate is a safe and effective mood stabilizer for patients with mania. Medknow Publications 2006 /pmc/articles/PMC2913561/ /pubmed/20703399 http://dx.doi.org/10.4103/0019-5545.31603 Text en © Indian Journal of Psychiatry http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Brief Research Communication
Solanki, R. K.
Singh, Paramjeet
Khandelwal, Renu
Midha, Aarti
Efficacy and tolerability of injectable sodium valproate in patients with mania
title Efficacy and tolerability of injectable sodium valproate in patients with mania
title_full Efficacy and tolerability of injectable sodium valproate in patients with mania
title_fullStr Efficacy and tolerability of injectable sodium valproate in patients with mania
title_full_unstemmed Efficacy and tolerability of injectable sodium valproate in patients with mania
title_short Efficacy and tolerability of injectable sodium valproate in patients with mania
title_sort efficacy and tolerability of injectable sodium valproate in patients with mania
topic Brief Research Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913561/
https://www.ncbi.nlm.nih.gov/pubmed/20703399
http://dx.doi.org/10.4103/0019-5545.31603
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AT khandelwalrenu efficacyandtolerabilityofinjectablesodiumvalproateinpatientswithmania
AT midhaaarti efficacyandtolerabilityofinjectablesodiumvalproateinpatientswithmania

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