The tumor suppressor gene KCTD11(REN )is regulated by Sp1 and methylation and its expression is reduced in tumors

A hallmark of several human cancers is loss of heterozygosity (LOH) of chromosome 17p13. The same chromosomal region is also frequently hypermethylated in cancer. Although loss of 17p13 has been often associated with p53 genetic alteration or Hypermethylated in Cancer 1 (HIC1) gene hypermethylation,...

Descripción completa

Detalles Bibliográficos
Autores principales: Mancarelli, M Michela, Zazzeroni, Francesca, Ciccocioppo, Lucia, Capece, Daria, Po, Agnese, Murgo, Simona, Di Camillo, Raffaello, Rinaldi, Christian, Ferretti, Elisabetta, Gulino, Alberto, Alesse, Edoardo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913982/
https://www.ncbi.nlm.nih.gov/pubmed/20591193
http://dx.doi.org/10.1186/1476-4598-9-172

Ejemplares similares

Ejemplares similares