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Evaluation of LMP1 of Epstein-Barr virus as a therapeutic target by its inhibition
BACKGROUND: The latent membrane protein-1 (LMP1) encoded by Epstein-Barr virus (EBV) is an oncoprotein which acts by constitutive activation of various signalling pathways, including NF-κB. In so doing it leads to deregulated cell growth intrinsic to the cancer cell as well as having extrinsic affec...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913984/ https://www.ncbi.nlm.nih.gov/pubmed/20618963 http://dx.doi.org/10.1186/1476-4598-9-184 |