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Evaluation of LMP1 of Epstein-Barr virus as a therapeutic target by its inhibition

BACKGROUND: The latent membrane protein-1 (LMP1) encoded by Epstein-Barr virus (EBV) is an oncoprotein which acts by constitutive activation of various signalling pathways, including NF-κB. In so doing it leads to deregulated cell growth intrinsic to the cancer cell as well as having extrinsic affec...

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Detalles Bibliográficos
Autores principales:	Hannigan, Adele, Wilson, Joanna B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913984/ https://www.ncbi.nlm.nih.gov/pubmed/20618963 http://dx.doi.org/10.1186/1476-4598-9-184

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