Cargando…

Elevation of sulfatides in ovarian cancer: An integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry

BACKGROUND: Sulfatides (ST) are a category of sulfated galactosylceramides (GalCer) that are elevated in many types of cancer including, possibly, ovarian cancer. Previous evidence for elevation of ST in ovarian cancer was based on a colorimetric reagent that does not provide structural details and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ying, Chen, Yanfeng, Momin, Amin, Shaner, Rebecca, Wang, Elaine, Bowen, Nathan J, Matyunina, Lilya V, Walker, L DeEtte, McDonald, John F, Sullards, M Cameron, Merrill, Alfred H
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2913985/ https://www.ncbi.nlm.nih.gov/pubmed/20624317 http://dx.doi.org/10.1186/1476-4598-9-186

Ejemplares similares

Transcriptional override: a regulatory network model of indirect responses to modulations in microRNA expression
por: Hill, Christopher G, et al.
Publicado: (2014)

Evidence for the Importance of Personalized Molecular Profiling in Pancreatic Cancer
por: Lili, Loukia N., et al.
Publicado: (2014)

Molecular Profiling Predicts the Existence of Two Functionally Distinct Classes of Ovarian Cancer Stroma
por: Lili, Loukia N., et al.
Publicado: (2013)

Evidence for the Complexity of MicroRNA-Mediated Regulation in Ovarian Cancer: A Systems Approach
por: Shahab, Shubin W., et al.
Publicado: (2011)

Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells
por: Bowen, Nathan J, et al.
Publicado: (2009)

Epigenetic changes within the promoter region of the HLA-G gene in ovarian tumors
por: Menendez, Laura, et al.
Publicado: (2008)

Identification of candidate methylation-responsive genes in ovarian cancer
por: Menendez, Laura, et al.
Publicado: (2007)

Molecular profiling supports the role of epithelial-to-mesenchymal transition (EMT) in ovarian cancer metastasis
por: Lili, Loukia N, et al.
Publicado: (2013)

Machine learning predicts individual cancer patient responses to therapeutic drugs with high accuracy
por: Huang, Cai, et al.
Publicado: (2018)

The effects of MicroRNA transfections on global patterns of gene expression in ovarian cancer cells are functionally coordinated
por: Shahab, Shubin W, et al.
Publicado: (2012)

Evidence for the importance of post-transcriptional regulatory changes in ovarian cancer progression and the contribution of miRNAs
por: Zhang, Mengnan, et al.
Publicado: (2017)

An Introduction to Sphingolipid Metabolism and Analysis by New Technologies
por: Chen, Yanfeng, et al.
Publicado: (2010)

LTR retrotransposons and the evolution of dosage compensation in Drosophila
por: Matyunina, Lilya V, et al.
Publicado: (2008)

The repertoire of protein-sulfatide interactions reveal distinct modes of sulfatide recognition
por: Capelluto, Daniel G. S
Publicado: (2022)

Polymorphonuclear Leukocyte Apoptosis Is Accelerated by Sulfatides or Sulfatides-Treated Salmonella Typhimurium Bacteria
por: Grishina, Zoryana V., et al.
Publicado: (2015)

Kdo(2)-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy
por: Sims, Kacee, et al.
Publicado: (2010)

Sulfatide Deficiency, an Early Alzheimer’s Lipidomic Signature, Causes Brain Ventricular Enlargement in the Absence of Classical Neuropathological Hallmarks
por: Palavicini, Juan Pablo, et al.
Publicado: (2022)

Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson’s disease primate model
por: Kaya, Ibrahim, et al.
Publicado: (2023)

Ovarian cancer detection from metabolomic liquid chromatography/mass spectrometry data by support vector machines
por: Guan, Wei, et al.
Publicado: (2009)

Circulating Sulfatide, A Novel Biomarker for ST-Segment Elevation Myocardial Infarction
por: Li, Gang, et al.
Publicado: (2019)

Snail-induced epithelial-to-mesenchymal transition of MCF-7 breast cancer cells: systems analysis of molecular changes and their effect on radiation and drug sensitivity
por: Mezencev, Roman, et al.
Publicado: (2016)

Immunological role of sulfatide in the pathogenesis of multiple sclerosis
por: Hamatani, Mio, et al.
Publicado: (2023)

Functional and Evolutionary Significance of Human MicroRNA Seed Region Mutations
por: Hill, Christopher G., et al.
Publicado: (2014)

Sulfatides Partition Disabled-2 in Response to Platelet Activation
por: Drahos, Karen E., et al.
Publicado: (2009)

Sulfatide levels correlate with severity of neuropathy in metachromatic leukodystrophy
por: Dali, Christine í, et al.
Publicado: (2015)

Probing sulfatide-tissue lectin recognition with functionalized glycodendrimersomes
por: Murphy, Paul V., et al.
Publicado: (2020)

HIGH RESOLUTION MASS SPECTROMETRY IN LIPIDOMICS
por: Züllig, Thomas, et al.
Publicado: (2020)

Evidence that p53-Mediated Cell-Cycle-Arrest Inhibits Chemotherapeutic Treatment of Ovarian Carcinomas
por: Moreno, Carlos S., et al.
Publicado: (2007)

Vitamin K enhances the production of brain sulfatides during remyelination
por: Popescu, Daniela C., et al.
Publicado: (2018)

Differential binding patterns of anti-sulfatide antibodies to glial membranes
por: Meehan, Gavin R., et al.
Publicado: (2018)

A method for visualization of “omic” datasets for sphingolipid metabolism to predict potentially interesting differences
por: Momin, Amin A., et al.
Publicado: (2011)

Galectin-4 and sulfatides in apical membrane trafficking in enterocyte-like cells
por: Delacour, Delphine, et al.
Publicado: (2005)

Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface
por: Buschard, Karsten, et al.
Publicado: (2016)

Conserved roles of C. elegans and human MANFs in sulfatide binding and cytoprotection
por: Bai, Meirong, et al.
Publicado: (2018)

The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide
por: Wang-Eckhardt, Lihua, et al.
Publicado: (2021)

Prognostic and immunological role of sulfatide-related lncRNAs in hepatocellular carcinoma
por: Huang, Xing Feng, et al.
Publicado: (2023)

Thematic Review Series: Sphingolipids. Biodiversity of sphingoid bases (“sphingosines”) and related amino alcohols
por: Pruett, Sarah T., et al.
Publicado: (2008)

Mass Spectrometry Based Lipidomics: An Overview of Technological Platforms
por: Köfeler, Harald C., et al.
Publicado: (2012)

Progress of Mass Spectrometry-Based Lipidomics in the Dairy Field
por: Ren, Wei, et al.
Publicado: (2023)

Uptake of the glycosphingolipid sulfatide in the gastrointestinal tract and pancreas in vivo and in isolated islets of Langerhans
por: Blomqvist, Maria, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_csg3e5afgrdvp6oi7qlof1pgdg