Plasmodium falciparum PfA-M1 aminopeptidase is trafficked via the parasitophorous vacuole and marginally delivered to the food vacuole

BACKGROUND: The Plasmodium falciparum PfA-M1 aminopeptidase, encoded by a single copy gene, displays a neutral optimal activity at pH 7.4. It is thought to be involved in haemoglobin degradation and/or invasion of the host cells. Although a series of inhibitors developed against PfA-M1 suggest that...

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Detalles Bibliográficos
Autores principales: Azimzadeh, Omid, Sow, Cissé, Gèze, Marc, Nyalwidhe, Julius, Florent, Isabelle
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914058/
https://www.ncbi.nlm.nih.gov/pubmed/20591164
http://dx.doi.org/10.1186/1475-2875-9-189

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