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Rationally improving LOV domain–based photoswitches

Genetically-encoded protein photosensors, including the LOV (light, oxygen, voltage) domain, are promising tools for engineering optical control of cellular behavior. We are only beginning to understand how to couple these light detectors to effectors of choice. We report a method that increases the...

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Detalles Bibliográficos
Autores principales: Strickland, Devin, Yao, Xiaolan, Gawlak, Grzegorz, Rosen, Michael K., Gardner, Kevin H., Sosnick, Tobin R.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914111/
https://www.ncbi.nlm.nih.gov/pubmed/20562867
http://dx.doi.org/10.1038/nmeth.1473