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A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer

Our case was 65 years old. At check-up, a high PSA level of 515 ng/ml was observed, the patient was diagnosed with having clinical stage D prostate cancer and a Maximum Androgen Blockade (MAB therapy) was started. In response to the exacerbated prostate cancer, we started a therapy involving the adm...

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Autores principales: Kawahara, Takashi, Taguchi, Hiroki, Yamagishi, Takuya, Udagawa, Koichi, Ouchi, Hideki, Misaki, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: S. Karger AG 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914385/
https://www.ncbi.nlm.nih.gov/pubmed/20737040
http://dx.doi.org/10.1159/000258964
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author Kawahara, Takashi
Taguchi, Hiroki
Yamagishi, Takuya
Udagawa, Koichi
Ouchi, Hideki
Misaki, Hiroshi
author_facet Kawahara, Takashi
Taguchi, Hiroki
Yamagishi, Takuya
Udagawa, Koichi
Ouchi, Hideki
Misaki, Hiroshi
author_sort Kawahara, Takashi
collection PubMed
description Our case was 65 years old. At check-up, a high PSA level of 515 ng/ml was observed, the patient was diagnosed with having clinical stage D prostate cancer and a Maximum Androgen Blockade (MAB therapy) was started. In response to the exacerbated prostate cancer, we started a therapy involving the administration of 8 mg/kg body weight of dexamethasone and 55 mg/m(2) of docetaxel every 3 weeks. After completing 8 courses, an enlargement of the bilateral adrenal tumor was observed, and after completing 12 courses, a pleural tumor was discovered and the PSA level was also increased. The patient was therefore diagnosed with having bilateral adrenal metastasis and pleural metastasis of prostate cancer through diagnostic imaging. So far, there have been no reports of multiple occurrences of prostate cancer in the adrenal glands and the pleura, thus making this case the first such case.
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spelling pubmed-29143852010-08-24 A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer Kawahara, Takashi Taguchi, Hiroki Yamagishi, Takuya Udagawa, Koichi Ouchi, Hideki Misaki, Hiroshi Case Rep Oncol Published: November 2009 Our case was 65 years old. At check-up, a high PSA level of 515 ng/ml was observed, the patient was diagnosed with having clinical stage D prostate cancer and a Maximum Androgen Blockade (MAB therapy) was started. In response to the exacerbated prostate cancer, we started a therapy involving the administration of 8 mg/kg body weight of dexamethasone and 55 mg/m(2) of docetaxel every 3 weeks. After completing 8 courses, an enlargement of the bilateral adrenal tumor was observed, and after completing 12 courses, a pleural tumor was discovered and the PSA level was also increased. The patient was therefore diagnosed with having bilateral adrenal metastasis and pleural metastasis of prostate cancer through diagnostic imaging. So far, there have been no reports of multiple occurrences of prostate cancer in the adrenal glands and the pleura, thus making this case the first such case. S. Karger AG 2009-11-21 /pmc/articles/PMC2914385/ /pubmed/20737040 http://dx.doi.org/10.1159/000258964 Text en Copyright © 2009 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No-Derivative-Works License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Users may download, print and share this work on the Internet for noncommercial purposes only, provided the original work is properly cited, and a link to the original work on http://www.karger.com and the terms of this license are included in any shared versions.
spellingShingle Published: November 2009
Kawahara, Takashi
Taguchi, Hiroki
Yamagishi, Takuya
Udagawa, Koichi
Ouchi, Hideki
Misaki, Hiroshi
A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer
title A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer
title_full A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer
title_fullStr A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer
title_full_unstemmed A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer
title_short A Case of Bilateral Adrenal and Pleural Metastases from Prostate Cancer
title_sort case of bilateral adrenal and pleural metastases from prostate cancer
topic Published: November 2009
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914385/
https://www.ncbi.nlm.nih.gov/pubmed/20737040
http://dx.doi.org/10.1159/000258964
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