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A Method for Individualizing the Prediction of Immunogenicity of Protein Vaccines and Biologic Therapeutics: Individualized T Cell Epitope Measure (iTEM)
The promise of pharmacogenomics depends on advancing predictive medicine. To address this need in the area of immunology, we developed the individualized T cell epitope measure (iTEM) tool to estimate an individual's T cell response to a protein antigen based on HLA binding predictions. In this...
Autores principales: | Cohen, Tobias, Moise, Leonard, Ardito, Matthew, Martin, William, De Groot, Anne S. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914454/ https://www.ncbi.nlm.nih.gov/pubmed/20706613 http://dx.doi.org/10.1155/2010/961752 |
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