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Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response

BACKGROUND: Recently, using a mouse model of mucopolysaccharidosis (MPS) IIIB, a lysosomal storage disease with severe neurological deterioration, we showed that MPS IIIB neuropathology is accompanied by a robust neuroinflammatory response of unknown consequence. This study was to assess whether MPS...

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Detalles Bibliográficos
Autores principales:	Killedar, Smruti, DiRosario, Julianne, Divers, Erin, Popovich, Phillip G, McCarty, Douglas M, Fu, Haiyan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914668/ https://www.ncbi.nlm.nih.gov/pubmed/20637096 http://dx.doi.org/10.1186/1742-2094-7-39

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