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Histamine H4 receptor antagonism diminishes existing airway inflammation and dysfunction via modulation of Th2 cytokines

BACKGROUND: Airway remodeling and dysfunction are characteristic features of asthma thought to be caused by aberrant production of Th2 cytokines. Histamine H(4 )receptor (H(4)R) perturbation has previously been shown to modify acute inflammation and Th2 cytokine production in a murine model of asthm...

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Detalles Bibliográficos
Autores principales:	Cowden, Jeffery M, Riley, Jason P, Ma, Jing Ying, Thurmond, Robin L, Dunford, Paul J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914735/ https://www.ncbi.nlm.nih.gov/pubmed/20573261 http://dx.doi.org/10.1186/1465-9921-11-86

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