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A Didactic Model of Macromolecular Crowding Effects on Protein Folding

A didactic model is presented to illustrate how the effect of macromolecular crowding on protein folding and association is modeled using current analytical theory and discrete molecular dynamics. While analytical treatments of crowding may consider the effect as a potential of average force acting...

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Detalles Bibliográficos
Autores principales: Tsao, Douglas, Minton, Allen P., Dokholyan, Nikolay V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914742/
https://www.ncbi.nlm.nih.gov/pubmed/20689808
http://dx.doi.org/10.1371/journal.pone.0011936

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