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Sensitivity of MEG and EEG to Source Orientation

An important difference between magnetoencephalography (MEG) and electroencephalography (EEG) is that MEG is insensitive to radially oriented sources. We quantified computationally the dependency of MEG and EEG on the source orientation using a forward model with realistic tissue boundaries. Similar...

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Detalles Bibliográficos
Autores principales: Ahlfors, Seppo P., Han, Jooman, Belliveau, John W., Hämäläinen, Matti S.
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914866/
https://www.ncbi.nlm.nih.gov/pubmed/20640882
http://dx.doi.org/10.1007/s10548-010-0154-x
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author Ahlfors, Seppo P.
Han, Jooman
Belliveau, John W.
Hämäläinen, Matti S.
author_facet Ahlfors, Seppo P.
Han, Jooman
Belliveau, John W.
Hämäläinen, Matti S.
author_sort Ahlfors, Seppo P.
collection PubMed
description An important difference between magnetoencephalography (MEG) and electroencephalography (EEG) is that MEG is insensitive to radially oriented sources. We quantified computationally the dependency of MEG and EEG on the source orientation using a forward model with realistic tissue boundaries. Similar to the simpler case of a spherical head model, in which MEG cannot see radial sources at all, for most cortical locations there was a source orientation to which MEG was insensitive. The median value for the ratio of the signal magnitude for the source orientation of the lowest and the highest sensitivity was 0.06 for MEG and 0.63 for EEG. The difference in the sensitivity to the source orientation is expected to contribute to systematic differences in the signal-to-noise ratio between MEG and EEG.
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spelling pubmed-29148662010-08-09 Sensitivity of MEG and EEG to Source Orientation Ahlfors, Seppo P. Han, Jooman Belliveau, John W. Hämäläinen, Matti S. Brain Topogr Original Paper An important difference between magnetoencephalography (MEG) and electroencephalography (EEG) is that MEG is insensitive to radially oriented sources. We quantified computationally the dependency of MEG and EEG on the source orientation using a forward model with realistic tissue boundaries. Similar to the simpler case of a spherical head model, in which MEG cannot see radial sources at all, for most cortical locations there was a source orientation to which MEG was insensitive. The median value for the ratio of the signal magnitude for the source orientation of the lowest and the highest sensitivity was 0.06 for MEG and 0.63 for EEG. The difference in the sensitivity to the source orientation is expected to contribute to systematic differences in the signal-to-noise ratio between MEG and EEG. Springer US 2010-07-18 2010 /pmc/articles/PMC2914866/ /pubmed/20640882 http://dx.doi.org/10.1007/s10548-010-0154-x Text en © The Author(s) 2010 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Paper
Ahlfors, Seppo P.
Han, Jooman
Belliveau, John W.
Hämäläinen, Matti S.
Sensitivity of MEG and EEG to Source Orientation
title Sensitivity of MEG and EEG to Source Orientation
title_full Sensitivity of MEG and EEG to Source Orientation
title_fullStr Sensitivity of MEG and EEG to Source Orientation
title_full_unstemmed Sensitivity of MEG and EEG to Source Orientation
title_short Sensitivity of MEG and EEG to Source Orientation
title_sort sensitivity of meg and eeg to source orientation
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914866/
https://www.ncbi.nlm.nih.gov/pubmed/20640882
http://dx.doi.org/10.1007/s10548-010-0154-x
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