3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one

In the mol­ecule of the title compound, C(22)H(22)ClN(3)O(2), the three fused rings of the benzofuro[3,2-d]pyrimidine system are almost coplanar. This ring system is oriented with respect to the substituted benzene ring at a dihedral angle of 79.05 (3)°. Intra­molecular C—H⋯N hydrogen bonding result...

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Detalles Bibliográficos
Autores principales: Liao, Quan-Bin, Li, Gui-Hua, Zhu, Zheng-Rong, Liu, Ming-Guo
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914975/
https://www.ncbi.nlm.nih.gov/pubmed/21200694
http://dx.doi.org/10.1107/S1600536807060412
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author Liao, Quan-Bin
Li, Gui-Hua
Zhu, Zheng-Rong
Liu, Ming-Guo
author_facet Liao, Quan-Bin
Li, Gui-Hua
Zhu, Zheng-Rong
Liu, Ming-Guo
author_sort Liao, Quan-Bin
collection PubMed
description In the mol­ecule of the title compound, C(22)H(22)ClN(3)O(2), the three fused rings of the benzofuro[3,2-d]pyrimidine system are almost coplanar. This ring system is oriented with respect to the substituted benzene ring at a dihedral angle of 79.05 (3)°. Intra­molecular C—H⋯N hydrogen bonding results in the formation of a six-membered ring. In the crystal structure, π–π stacking inter­actions involving the furan, pyrimidinone and benzene rings are present [centroid-to-centroid distances in the range 3.258 (1)–3.870 (1) Å].
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spelling pubmed-29149752010-12-30 3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one Liao, Quan-Bin Li, Gui-Hua Zhu, Zheng-Rong Liu, Ming-Guo Acta Crystallogr Sect E Struct Rep Online Organic Papers In the mol­ecule of the title compound, C(22)H(22)ClN(3)O(2), the three fused rings of the benzofuro[3,2-d]pyrimidine system are almost coplanar. This ring system is oriented with respect to the substituted benzene ring at a dihedral angle of 79.05 (3)°. Intra­molecular C—H⋯N hydrogen bonding results in the formation of a six-membered ring. In the crystal structure, π–π stacking inter­actions involving the furan, pyrimidinone and benzene rings are present [centroid-to-centroid distances in the range 3.258 (1)–3.870 (1) Å]. International Union of Crystallography 2007-12-06 /pmc/articles/PMC2914975/ /pubmed/21200694 http://dx.doi.org/10.1107/S1600536807060412 Text en © International Union of Crystallography 2008 http://journals.iucr.org/services/termsofuse.html This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html.
spellingShingle Organic Papers
Liao, Quan-Bin
Li, Gui-Hua
Zhu, Zheng-Rong
Liu, Ming-Guo
3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one
title 3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one
title_full 3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one
title_fullStr 3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one
title_full_unstemmed 3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one
title_short 3-(4-Chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3H)-one
title_sort 3-(4-chloro­phen­yl)-2-(diisopropyl­amino)-1-benzofuro[3,2-d]pyrimidin-4(3h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914975/
https://www.ncbi.nlm.nih.gov/pubmed/21200694
http://dx.doi.org/10.1107/S1600536807060412
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