l-Nebiviololinium chloride dihydrate

The hydro­chloride salt of chiral l-nebivolol {systematic name: (+)−(R,S,S,S)-bis­[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxy­ethyl]ammonium chloride dihydrate}, C(22)H(26)F(2)NO(4) (+)·Cl(−)·2H(2)O, was obtained by chiral liquid chromatography as a dihydrate. The pyran rings adopt half...

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Detalles Bibliográficos
Autores principales: Tuchalski, Gisbert, Hänsicke, Andre, Reck, Günther, Emmerling, Franziska
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915012/
https://www.ncbi.nlm.nih.gov/pubmed/21200930
http://dx.doi.org/10.1107/S1600536807061831
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author Tuchalski, Gisbert
Hänsicke, Andre
Reck, Günther
Emmerling, Franziska
author_facet Tuchalski, Gisbert
Hänsicke, Andre
Reck, Günther
Emmerling, Franziska
author_sort Tuchalski, Gisbert
collection PubMed
description The hydro­chloride salt of chiral l-nebivolol {systematic name: (+)−(R,S,S,S)-bis­[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxy­ethyl]ammonium chloride dihydrate}, C(22)H(26)F(2)NO(4) (+)·Cl(−)·2H(2)O, was obtained by chiral liquid chromatography as a dihydrate. The pyran rings adopt half-chair conformations. Hydrogen bonds between the cation, anions and water mol­ecules contribute to the formation of layers parallel to the ac plane.
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spelling pubmed-29150122010-12-30 l-Nebiviololinium chloride dihydrate Tuchalski, Gisbert Hänsicke, Andre Reck, Günther Emmerling, Franziska Acta Crystallogr Sect E Struct Rep Online Organic Papers The hydro­chloride salt of chiral l-nebivolol {systematic name: (+)−(R,S,S,S)-bis­[2-(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)-2-hydroxy­ethyl]ammonium chloride dihydrate}, C(22)H(26)F(2)NO(4) (+)·Cl(−)·2H(2)O, was obtained by chiral liquid chromatography as a dihydrate. The pyran rings adopt half-chair conformations. Hydrogen bonds between the cation, anions and water mol­ecules contribute to the formation of layers parallel to the ac plane. International Union of Crystallography 2007-12-06 /pmc/articles/PMC2915012/ /pubmed/21200930 http://dx.doi.org/10.1107/S1600536807061831 Text en © International Union of Crystallography 2008 http://journals.iucr.org/services/termsofuse.html This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html.
spellingShingle Organic Papers
Tuchalski, Gisbert
Hänsicke, Andre
Reck, Günther
Emmerling, Franziska
l-Nebiviololinium chloride dihydrate
title l-Nebiviololinium chloride dihydrate
title_full l-Nebiviololinium chloride dihydrate
title_fullStr l-Nebiviololinium chloride dihydrate
title_full_unstemmed l-Nebiviololinium chloride dihydrate
title_short l-Nebiviololinium chloride dihydrate
title_sort l-nebiviololinium chloride dihydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915012/
https://www.ncbi.nlm.nih.gov/pubmed/21200930
http://dx.doi.org/10.1107/S1600536807061831
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AT hansickeandre lnebiviololiniumchloridedihydrate
AT reckgunther lnebiviololiniumchloridedihydrate
AT emmerlingfranziska lnebiviololiniumchloridedihydrate

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