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Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1)
In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimethoxy pyrimidine molecules interact with the carboxylic group of the respective anthranilic aci...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915181/ https://www.ncbi.nlm.nih.gov/pubmed/21200672 http://dx.doi.org/10.1107/S1600536807063271 |
Sumario: | In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimethoxy pyrimidine molecules interact with the carboxylic group of the respective anthranilic acid molecules through N—H⋯O and O—H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded motif R (2) (2)(8). The pyrimidine molecules also form base pairs via a pair of N—H⋯N hydrogen bonds, forming another R (2) (2)(8) motif. The typical intramolecular N—H⋯O hydrogen bond is observed in the anthranilic acid molecules. Furthermore, the crystal structure is stabilized by C—H⋯O hydrogen bonds. |
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