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Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1)
In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimethoxy pyrimidine molecules interact with the carboxylic group of the respective anthranilic aci...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915181/ https://www.ncbi.nlm.nih.gov/pubmed/21200672 http://dx.doi.org/10.1107/S1600536807063271 |
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author | Thanigaimani, Kaliyaperumal Muthiah, Packianathan Thomas Lynch, Daniel E. |
author_facet | Thanigaimani, Kaliyaperumal Muthiah, Packianathan Thomas Lynch, Daniel E. |
author_sort | Thanigaimani, Kaliyaperumal |
collection | PubMed |
description | In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimethoxy pyrimidine molecules interact with the carboxylic group of the respective anthranilic acid molecules through N—H⋯O and O—H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded motif R (2) (2)(8). The pyrimidine molecules also form base pairs via a pair of N—H⋯N hydrogen bonds, forming another R (2) (2)(8) motif. The typical intramolecular N—H⋯O hydrogen bond is observed in the anthranilic acid molecules. Furthermore, the crystal structure is stabilized by C—H⋯O hydrogen bonds. |
format | Text |
id | pubmed-2915181 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29151812010-12-30 Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) Thanigaimani, Kaliyaperumal Muthiah, Packianathan Thomas Lynch, Daniel E. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimethoxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimethoxy pyrimidine molecules interact with the carboxylic group of the respective anthranilic acid molecules through N—H⋯O and O—H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded motif R (2) (2)(8). The pyrimidine molecules also form base pairs via a pair of N—H⋯N hydrogen bonds, forming another R (2) (2)(8) motif. The typical intramolecular N—H⋯O hydrogen bond is observed in the anthranilic acid molecules. Furthermore, the crystal structure is stabilized by C—H⋯O hydrogen bonds. International Union of Crystallography 2007-12-06 /pmc/articles/PMC2915181/ /pubmed/21200672 http://dx.doi.org/10.1107/S1600536807063271 Text en © International Union of Crystallography 2008 http://journals.iucr.org/services/termsofuse.html This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html. |
spellingShingle | Organic Papers Thanigaimani, Kaliyaperumal Muthiah, Packianathan Thomas Lynch, Daniel E. Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
title | Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
title_full | Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
title_fullStr | Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
title_full_unstemmed | Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
title_short | Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
title_sort | hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxypyrimidine–anthranilic acid (1/1) |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915181/ https://www.ncbi.nlm.nih.gov/pubmed/21200672 http://dx.doi.org/10.1107/S1600536807063271 |
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