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Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)

In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimeth­oxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimeth­oxy pyrimidine mol­ecules inter­act with the carboxylic group of the respective anthranilic aci...

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Detalles Bibliográficos
Autores principales: Thanigaimani, Kaliyaperumal, Muthiah, Packianathan Thomas, Lynch, Daniel E.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915181/
https://www.ncbi.nlm.nih.gov/pubmed/21200672
http://dx.doi.org/10.1107/S1600536807063271
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author Thanigaimani, Kaliyaperumal
Muthiah, Packianathan Thomas
Lynch, Daniel E.
author_facet Thanigaimani, Kaliyaperumal
Muthiah, Packianathan Thomas
Lynch, Daniel E.
author_sort Thanigaimani, Kaliyaperumal
collection PubMed
description In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimeth­oxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimeth­oxy pyrimidine mol­ecules inter­act with the carboxylic group of the respective anthranilic acid mol­ecules through N—H⋯O and O—H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded motif R (2) (2)(8). The pyrimidine mol­ecules also form base pairs via a pair of N—H⋯N hydrogen bonds, forming another R (2) (2)(8) motif. The typical intra­molecular N—H⋯O hydrogen bond is observed in the anthranilic acid mol­ecules. Furthermore, the crystal structure is stabilized by C—H⋯O hydrogen bonds.
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spelling pubmed-29151812010-12-30 Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1) Thanigaimani, Kaliyaperumal Muthiah, Packianathan Thomas Lynch, Daniel E. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title cocrystal, C(6)H(9)N(3)O(2)·C(7)H(7)NO(2), the asymmetric unit contains two crystallographically independent 2-amino-4,6-dimeth­oxy pyrimidine-anthranilic acid adducts. The 2-amino-4,6-dimeth­oxy pyrimidine mol­ecules inter­act with the carboxylic group of the respective anthranilic acid mol­ecules through N—H⋯O and O—H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded motif R (2) (2)(8). The pyrimidine mol­ecules also form base pairs via a pair of N—H⋯N hydrogen bonds, forming another R (2) (2)(8) motif. The typical intra­molecular N—H⋯O hydrogen bond is observed in the anthranilic acid mol­ecules. Furthermore, the crystal structure is stabilized by C—H⋯O hydrogen bonds. International Union of Crystallography 2007-12-06 /pmc/articles/PMC2915181/ /pubmed/21200672 http://dx.doi.org/10.1107/S1600536807063271 Text en © International Union of Crystallography 2008 http://journals.iucr.org/services/termsofuse.html This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html.
spellingShingle Organic Papers
Thanigaimani, Kaliyaperumal
Muthiah, Packianathan Thomas
Lynch, Daniel E.
Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
title Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
title_full Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
title_fullStr Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
title_full_unstemmed Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
title_short Hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
title_sort hydrogen-bonding patterns in the cocrystal 2-amino-4,6-dimethoxy­pyrimidine–anthranilic acid (1/1)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915181/
https://www.ncbi.nlm.nih.gov/pubmed/21200672
http://dx.doi.org/10.1107/S1600536807063271
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