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3-Ethyl-2-methyl-5-methyl­ene-6,7-di­hydroindol-4(5H)-one

The title compound, C(12)H(15)NO, a degradation product of molindone hydro­chloride, was prepared by the reaction of molindone with methyl iodide and subsequent reaction of the resulting quaternary ammonium salt with 2N aqueous sodium hydroxide. The newly formed double bond is exocyclic in nature an...

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Detalles Bibliográficos
Autores principales: Sonar, Vijayakumar N., Parkin, Sean, Crooks, Peter A.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915226/
https://www.ncbi.nlm.nih.gov/pubmed/21200723
http://dx.doi.org/10.1107/S1600536807063076
Descripción
Sumario:The title compound, C(12)H(15)NO, a degradation product of molindone hydro­chloride, was prepared by the reaction of molindone with methyl iodide and subsequent reaction of the resulting quaternary ammonium salt with 2N aqueous sodium hydroxide. The newly formed double bond is exocyclic in nature and the carbonyl group is conjugated with the π-electrons of the pyrrole ring. The six-membered ring is in the half-chair conformation. The H atom attached to the N atom is involved in an inter­molecular hydrogen bond with the O atom of a screw-related mol­ecule, thus forming a continuous chain.