2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide

The title compound, C(17)H(23)NO(2), contains two chiral centres and was synthesized from 2-(3-acetyl-2,2-dimethyl­cyclo­butyl)acetic acid and m-toluidine. The cyclobutane ring is not flat but flexed as though folded from the dimethyl-substituted C atom to the unsubstituted C atom, with a dihedral a...

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Detalles Bibliográficos
Autores principales: Yin, Yan-Bai, Song, Zhan-Qian, Wang, Zong-De, Shang, Shi-Bin
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2007
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915342/
https://www.ncbi.nlm.nih.gov/pubmed/21200856
http://dx.doi.org/10.1107/S160053680706641X
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author Yin, Yan-Bai
Song, Zhan-Qian
Wang, Zong-De
Shang, Shi-Bin
author_facet Yin, Yan-Bai
Song, Zhan-Qian
Wang, Zong-De
Shang, Shi-Bin
author_sort Yin, Yan-Bai
collection PubMed
description The title compound, C(17)H(23)NO(2), contains two chiral centres and was synthesized from 2-(3-acetyl-2,2-dimethyl­cyclo­butyl)acetic acid and m-toluidine. The cyclobutane ring is not flat but flexed as though folded from the dimethyl-substituted C atom to the unsubstituted C atom, with a dihedral angle of 25.9°. The crystal structure is stabilized by N—H⋯O and C—H⋯O hydrogen-bonding inter­actions.
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spelling pubmed-29153422010-12-30 2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide Yin, Yan-Bai Song, Zhan-Qian Wang, Zong-De Shang, Shi-Bin Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(17)H(23)NO(2), contains two chiral centres and was synthesized from 2-(3-acetyl-2,2-dimethyl­cyclo­butyl)acetic acid and m-toluidine. The cyclobutane ring is not flat but flexed as though folded from the dimethyl-substituted C atom to the unsubstituted C atom, with a dihedral angle of 25.9°. The crystal structure is stabilized by N—H⋯O and C—H⋯O hydrogen-bonding inter­actions. International Union of Crystallography 2007-12-18 /pmc/articles/PMC2915342/ /pubmed/21200856 http://dx.doi.org/10.1107/S160053680706641X Text en © Yin et al. 2008 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Yin, Yan-Bai
Song, Zhan-Qian
Wang, Zong-De
Shang, Shi-Bin
2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide
title 2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide
title_full 2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide
title_fullStr 2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide
title_full_unstemmed 2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide
title_short 2-[(1S,3S)-3-Acetyl-2,2-dimethyl­cyclo­butyl]-N-(m-tol­yl)acetamide
title_sort 2-[(1s,3s)-3-acetyl-2,2-dimethyl­cyclo­butyl]-n-(m-tol­yl)acetamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915342/
https://www.ncbi.nlm.nih.gov/pubmed/21200856
http://dx.doi.org/10.1107/S160053680706641X
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AT songzhanqian 21s3s3acetyl22dimethylcyclobutylnmtolylacetamide
AT wangzongde 21s3s3acetyl22dimethylcyclobutylnmtolylacetamide
AT shangshibin 21s3s3acetyl22dimethylcyclobutylnmtolylacetamide

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