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Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
The title compound, C(18)H(19)NO(5), is a product of the Hantzsch reaction of p-phthalaldehyde, methyl acetoacetate, and ammonium acetate. The 1,4-dihydropyridine ring of the molecule adopts a flattened boat conformation. The benzene ring is almost perpendicular to the 1,4-dihydropyridine ring; t...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915344/ https://www.ncbi.nlm.nih.gov/pubmed/21200858 http://dx.doi.org/10.1107/S1600536807063428 |
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author | Teng, Fei Kong, Fanpeng Liu, Qingjian |
author_facet | Teng, Fei Kong, Fanpeng Liu, Qingjian |
author_sort | Teng, Fei |
collection | PubMed |
description | The title compound, C(18)H(19)NO(5), is a product of the Hantzsch reaction of p-phthalaldehyde, methyl acetoacetate, and ammonium acetate. The 1,4-dihydropyridine ring of the molecule adopts a flattened boat conformation. The benzene ring is almost perpendicular to the 1,4-dihydropyridine ring; the plane through the six C atoms of the benzene ring and the plane through the four C atoms that form the base of the boat-shaped 1,4-dihydropyridine ring (excluding the ring N atom and the opposite ring C atom) make a dihedral angle of 87.60 (3)°. Intermolecular N—H⋯O hydrogen bonds result in the formation of extended chains along the a axis. |
format | Text |
id | pubmed-2915344 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2007 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29153442010-12-30 Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate Teng, Fei Kong, Fanpeng Liu, Qingjian Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(18)H(19)NO(5), is a product of the Hantzsch reaction of p-phthalaldehyde, methyl acetoacetate, and ammonium acetate. The 1,4-dihydropyridine ring of the molecule adopts a flattened boat conformation. The benzene ring is almost perpendicular to the 1,4-dihydropyridine ring; the plane through the six C atoms of the benzene ring and the plane through the four C atoms that form the base of the boat-shaped 1,4-dihydropyridine ring (excluding the ring N atom and the opposite ring C atom) make a dihedral angle of 87.60 (3)°. Intermolecular N—H⋯O hydrogen bonds result in the formation of extended chains along the a axis. International Union of Crystallography 2007-12-18 /pmc/articles/PMC2915344/ /pubmed/21200858 http://dx.doi.org/10.1107/S1600536807063428 Text en © International Union of Crystallography 2008 http://journals.iucr.org/services/termsofuse.html This is an open-access article distributed under the terms described at http://journals.iucr.org/services/termsofuse.html. |
spellingShingle | Organic Papers Teng, Fei Kong, Fanpeng Liu, Qingjian Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title | Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_full | Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_fullStr | Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_full_unstemmed | Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_short | Dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
title_sort | dimethyl 4-(4-formylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915344/ https://www.ncbi.nlm.nih.gov/pubmed/21200858 http://dx.doi.org/10.1107/S1600536807063428 |
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