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Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)](4)

Guanine-rich nucleic acid sequences can adopt G-quadruplex structures stabilized by layers of four Hoogsteen-paired guanine residues. Quadruplex-prone sequences are found in many regions of human genome and in the telomeres of all eukaryotic organisms. Since small molecules that target G-quadruplexe...

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Detalles Bibliográficos
Autores principales:	Pagano, Bruno, Fotticchia, Iolanda, De Tito, Stefano, Mattia, Carlo A., Mayol, Luciano, Novellino, Ettore, Randazzo, Antonio, Giancola, Concetta
Formato:	Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915651/ https://www.ncbi.nlm.nih.gov/pubmed/20725616 http://dx.doi.org/10.4061/2010/247137

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