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Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey
OBJECTIVE: To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP). METHODS: A computerized device (Travalert(®)) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were decl...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915860/ https://www.ncbi.nlm.nih.gov/pubmed/20689790 |
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author | Nordmann, Jean-Philippe Baudouin, Christophe Renard, Jean-Paul Denis, Philippe Lafuma, Antoine Laurendeau, Caroline Jeanbat, Viviane Berdeaux, Gilles |
author_facet | Nordmann, Jean-Philippe Baudouin, Christophe Renard, Jean-Paul Denis, Philippe Lafuma, Antoine Laurendeau, Caroline Jeanbat, Viviane Berdeaux, Gilles |
author_sort | Nordmann, Jean-Philippe |
collection | PubMed |
description | OBJECTIVE: To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP). METHODS: A computerized device (Travalert(®)) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were declared compliant when at least 2 drops were instilled per day. Compliance rates were calculated for weekdays and weekends, separately, over 8 consecutive weeks. A principal components analysis (PCA) was followed by an ascendant hierarchical classification (AHC) to identify compliance groups. RESULTS: 140 patients were recruited (mean age 65.5 years; 51.8% female) of whom 83.6% had primary open-angle glaucoma with mean IOP 23.9 mmHg before Travalert(®) use. 60.7% were treated with DuoTrav(®) (travoprost timolol fixed combination) and 39.3% with travoprost. The PCA identified two axes (compliance and treatment weeks). The AHC identified 3 compliance groups: ‘high’ (56.6%, approx. 80% compliance), ‘medium’ (21.2%, approx. 50% compliance), and ‘low’ (22.1%, approx. 20% compliance). Demographics and glaucoma parameters did not predict low compliance. Final mean IOP was 16.1 mmHg, but higher in the low compliance group (17.7 mmHg, P = 0.02). CONCLUSIONS: Compliance measurement by a medical device showed compliance rates <80% by 50% (approx.) of patients, significantly impacting IOP control. No demographic or glaucoma variable was associated with low compliance. |
format | Text |
id | pubmed-2915860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-29158602010-08-04 Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey Nordmann, Jean-Philippe Baudouin, Christophe Renard, Jean-Paul Denis, Philippe Lafuma, Antoine Laurendeau, Caroline Jeanbat, Viviane Berdeaux, Gilles Clin Ophthalmol Original Research OBJECTIVE: To identify and characterize treatment compliance profiles of glaucoma patients and evaluate the association with intraocular pressure (IOP). METHODS: A computerized device (Travalert(®)) that recorded daily instillation times and eye-drop counts was given for 3 months. Patients were declared compliant when at least 2 drops were instilled per day. Compliance rates were calculated for weekdays and weekends, separately, over 8 consecutive weeks. A principal components analysis (PCA) was followed by an ascendant hierarchical classification (AHC) to identify compliance groups. RESULTS: 140 patients were recruited (mean age 65.5 years; 51.8% female) of whom 83.6% had primary open-angle glaucoma with mean IOP 23.9 mmHg before Travalert(®) use. 60.7% were treated with DuoTrav(®) (travoprost timolol fixed combination) and 39.3% with travoprost. The PCA identified two axes (compliance and treatment weeks). The AHC identified 3 compliance groups: ‘high’ (56.6%, approx. 80% compliance), ‘medium’ (21.2%, approx. 50% compliance), and ‘low’ (22.1%, approx. 20% compliance). Demographics and glaucoma parameters did not predict low compliance. Final mean IOP was 16.1 mmHg, but higher in the low compliance group (17.7 mmHg, P = 0.02). CONCLUSIONS: Compliance measurement by a medical device showed compliance rates <80% by 50% (approx.) of patients, significantly impacting IOP control. No demographic or glaucoma variable was associated with low compliance. Dove Medical Press 2010 2010-07-30 /pmc/articles/PMC2915860/ /pubmed/20689790 Text en © 2010 Nordmann et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Original Research Nordmann, Jean-Philippe Baudouin, Christophe Renard, Jean-Paul Denis, Philippe Lafuma, Antoine Laurendeau, Caroline Jeanbat, Viviane Berdeaux, Gilles Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
title | Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
title_full | Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
title_fullStr | Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
title_full_unstemmed | Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
title_short | Measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
title_sort | measurement of treatment compliance using a medical device for glaucoma patients associated with intraocular pressure control: a survey |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915860/ https://www.ncbi.nlm.nih.gov/pubmed/20689790 |
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