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True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair

Nucleotide excision repair (NER) is a major DNA repair pathway in eukaryotic cells. NER removes structurally diverse lesions such as pyrimidine dimers, arising upon UV irradiation or bulky chemical adducts, arising upon exposure to carcinogens and some chemotherapeutic drugs. NER defects lead to thr...

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Detalles Bibliográficos
Autores principales: Le May, Nicolas, Egly, Jean-Marc, Coin, Frédéric
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915888/
https://www.ncbi.nlm.nih.gov/pubmed/20725631
http://dx.doi.org/10.4061/2010/616342