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An Unbiased Estimator of Gene Diversity in Samples Containing Related Individuals

Gene diversity is sometimes estimated from samples that contain inbred or related individuals. If inbred or related individuals are included in a sample, then the standard estimator for gene diversity produces a downward bias caused by an inflation of the variance of estimated allele frequencies. We...

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Detalles Bibliográficos
Autores principales: DeGiorgio, Michael, Rosenberg, Noah A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915906/
https://www.ncbi.nlm.nih.gov/pubmed/18988687
http://dx.doi.org/10.1093/molbev/msn254