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Fibronectin and laminin promote differentiation of human mesenchymal stem cells into insulin producing cells through activating Akt and ERK

BACKGROUND: Islet transplantation provides a promising cure for Type 1 diabetes; however it is limited by a shortage of pancreas donors. Bone marrow-derived multipotent mesenchymal stem cells (MSCs) offer renewable cells for generating insulin-producing cells (IPCs). METHODS: We used a four-stage di...

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Detalles Bibliográficos
Autores principales:	Lin, Hsiao-Yun, Tsai, Chih-Chien, Chen, Ling-Lan, Chiou, Shih-Hwa, Wang, Yng-Jiin, Hung, Shih-Chieh
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2915967/ https://www.ncbi.nlm.nih.gov/pubmed/20624296 http://dx.doi.org/10.1186/1423-0127-17-56

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