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Munc13 C(2)B-Domain – an Activity-Dependent Ca(2+)-Regulator of Synaptic Exocytosis

Munc13 is a multidomain protein of presynaptic active zones that mediates the priming and plasticity of synaptic vesicle exocytosis, but the mechanisms involved remain unclear. Here, we use biophysical, biochemical, and electrophysiological approaches to demonstrate that the central C(2)B-domain of...

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Detalles Bibliográficos
Autores principales:	Shin, Ok-Ho, Lu, Jun, Rhee, Jeong-Seop, Tomchick, Diana R., Pang, Zhiping P., Wojcik, Sonja, Camacho-Perez, Marcial, Brose, Nils, Machius, Mischa, Rizo, Josep, Rosenmund, Christian, Südhof, Thomas C.
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916016/ https://www.ncbi.nlm.nih.gov/pubmed/20154707 http://dx.doi.org/10.1038/nsmb.1758

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