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Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes
PURPOSE: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). METHODS: Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Corre...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Ophthalmological Society
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916102/ https://www.ncbi.nlm.nih.gov/pubmed/20714384 http://dx.doi.org/10.3341/kjo.2010.24.4.213 |
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author | Chung, Song Ee Lim, Dong Hui Kang, Se Woong Yoon, Young Hee Chae, Ju Byung Roh, In Ho |
author_facet | Chung, Song Ee Lim, Dong Hui Kang, Se Woong Yoon, Young Hee Chae, Ju Byung Roh, In Ho |
author_sort | Chung, Song Ee |
collection | PubMed |
description | PURPOSE: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). METHODS: Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (V(postop), logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters: the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced. RESULTS: V(postop) was determined to be significantly correlated with the preoperative visual acuity (V(preop)) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of V(postop) was derived from the most accurate regression analysis: V(postop)=0.248×V(preop)+1.1×10(-6)×A(2)-0.121×D+0.19. CONCLUSIONS: The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer. |
format | Text |
id | pubmed-2916102 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | The Korean Ophthalmological Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-29161022010-08-16 Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes Chung, Song Ee Lim, Dong Hui Kang, Se Woong Yoon, Young Hee Chae, Ju Byung Roh, In Ho Korean J Ophthalmol Original Article PURPOSE: To identify the correlation between preoperative optical coherence tomography (OCT) features and postoperative visual outcomes in eyes with idiopathic macular holes (MHs). METHODS: Data from 55 eyes with idiopathic MHs which had been sealed by vitrectomy were retrospectively reviewed. Correlation analysis was conducted between postoperative visual acuity (V(postop), logarithm of the minimum angle of resolution [logMAR]) and preoperative factors, including four OCT parameters: the anticipated length (A) devoid of photoreceptors after hole closure, MH height (B), MH size (C), and the grading (D) of the viability of detached photoreceptors. Additionally, the formula for the prediction of visual outcome was deduced. RESULTS: V(postop) was determined to be significantly correlated with the preoperative visual acuity (V(preop)) and OCT parameters A, C, and D (p<0.001). Based on the correlation, the formula for the prediction of V(postop) was derived from the most accurate regression analysis: V(postop)=0.248×V(preop)+1.1×10(-6)×A(2)-0.121×D+0.19. CONCLUSIONS: The length and viability of detached photoreceptors are significant preoperative OCT features for predicting visual prognosis. This suggests that, regardless of the MH size and symptom duration, active surgical intervention should be encouraged, particularly if the MH exhibits good viability in the detached photoreceptor layer. The Korean Ophthalmological Society 2010-08 2010-08-03 /pmc/articles/PMC2916102/ /pubmed/20714384 http://dx.doi.org/10.3341/kjo.2010.24.4.213 Text en © 2010 The Korean Ophthalmological Society http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Chung, Song Ee Lim, Dong Hui Kang, Se Woong Yoon, Young Hee Chae, Ju Byung Roh, In Ho Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes |
title | Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes |
title_full | Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes |
title_fullStr | Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes |
title_full_unstemmed | Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes |
title_short | Central Photoreceptor Viability and Prediction of Visual Outcome in Patients with Idiopathic Macular Holes |
title_sort | central photoreceptor viability and prediction of visual outcome in patients with idiopathic macular holes |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916102/ https://www.ncbi.nlm.nih.gov/pubmed/20714384 http://dx.doi.org/10.3341/kjo.2010.24.4.213 |
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