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A Novel Doxorubicin Prodrug with Controllable Photolysis Activation for Cancer Chemotherapy
PURPOSE: Doxorubicin (DOX) is a very effective anticancer agent. However, in its pure form, its application is limited by significant cardiotoxic side effects. The purpose of this study was to develop a controllably activatable chemotherapy prodrug of DOX created by blocking its free amine group wit...
Autores principales: | Ibsen, Stuart, Zahavy, Eran, Wrasdilo, Wolf, Berns, Michael, Chan, Michael, Esener, Sadik |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916115/ https://www.ncbi.nlm.nih.gov/pubmed/20596761 http://dx.doi.org/10.1007/s11095-010-0183-x |
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