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Hydrophilic Polyester Microspheres: Effect of Molecular Weight and Copolymer Composition on Release of BSA
PURPOSE: To study the release of a model protein, bovine serum albumin (BSA), from microspheres of an hydroxylated aliphatic polyester, poly(lactic-co-hydroxymethyl glycolic acid) (PLHMGA). METHODS: BSA-loaded microspheres were prepared by a double emulsion solvent evaporation method. The effect of...
Autores principales: | Ghassemi, Amir H., van Steenbergen, Mies J., Talsma, Herre, van Nostrum, Cornelus F., Crommelin, Daan J. A., Hennink, Wim E. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer US
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916118/ https://www.ncbi.nlm.nih.gov/pubmed/20602152 http://dx.doi.org/10.1007/s11095-010-0205-8 |
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