Myeloid cells, BAFF, and IFN-γ establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice

Autoimmunity is traditionally attributed to altered lymphoid cell selection and/or tolerance, whereas the contribution of innate immune cells is less well understood. Autoimmunity is also associated with increased levels of B cell–activating factor of the TNF family (BAFF; also known as B lymphocyte...

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Detalles Bibliográficos
Autores principales: Scapini, Patrizia, Hu, Yongmei, Chu, Ching-Liang, Migone, Thi-Sau, DeFranco, Anthony L., Cassatella, Marco A., Lowell, Clifford A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916124/
https://www.ncbi.nlm.nih.gov/pubmed/20624892
http://dx.doi.org/10.1084/jem.20100086

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